Antimicrobial, antioxidant, and angiogenic bioactive silver nanoparticles produced using <i>Murraya paniculata</i> (L.) jack leaves

Murraya paniculata (MP) can be used as a reducing agent to produce silver nanoparticles (AgNPs) using simple procedure. AgNPs are characterized in morphological and chemical properties, antioxidant activity, cytotoxicity. The morphology of derived from MP shows face-centered cubic structure, spherical shape with an average particle size 23 nm. structure characteristic peaks UV-vis spectrometer at 438 formation is confirmed by analyzing their vibrational states under infrared radiation; typical recognized: 3429 cm −1 (O-H stretch, H-bonded alcohols, phenols groups), 2923 (C-H stretch alkanes), 1626 (N-H bend 1° amines), 1583 (C-C ring aromatic), 1039 (C-N aliphatic 728 (C-Cl alkyl halides), 589 (C-Br respectively. produced show activity They the highest sensitivity toward Bacillus cereus. Cytotoxicity biosynthesized AgNPs, determined scratch wound assay on vitro human endothelial vein cell, created showed dose-dependent activity. These concentration 15.625 μg/mL, stimulate proliferation migration cells (EC) showing angiogenic